Docteur André GIBERT - Hépato- Gastro- Entérologie
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nouveau traitement pour l'éradication d'Helicobacter pylori (Megraud F. Therap Adv Gastroenterol. 2012

 Helicobacter pylori (Hp) est considéré comme un carcinogène par l'Organisation mondiale de la santé (OMS). l'éradication de la bactérie s'est développée de manière exponentielle depuis les années 1980 et est associée à la survenue rapide de résistances aux antibiotiques, en particulier à la clarythromycine, dont les taux dépassent actuellement 35% en France. Si bien que les protocoles d'éradication ont été amenés à évoluer vers des triples associations, voire maintenant des thérapies séquentielles. l'autorisation de mise sur le marché, d'une association reposant sur le sous-citrate de bismuth, le métronidazole et la tétracycline sera très vite considérée comme la référence pour l'éradication, avec des taux de succès atteignant plus de 85% suivant les études récentes. la pharmacovigilance aux Etats-Unis n'a pas conduit à identifier des effets secondaires de type neurologique depuis 2008. Un nouveau médicament en gastro-entérologie attendu pour le mois d'avril 2013 !

122 commentaires pour nouveau traitement pour l'éradication d'Helicobacter pylori (Megraud F. Therap Adv Gastroenterol. 2012:

Commentaires RSS
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